HRM 635 Topic 1 DQ 2 Define clinical significance, and explain the difference between clinical and statistical significance

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A Sample Answer For the Assignment: HRM 635 Topic 1 DQ 2 Define clinical significance, and explain the difference between clinical and statistical significance

Title: HRM 635 Topic 1 DQ 2 Define clinical significance, and explain the difference between clinical and statistical significance

HRM 635 Topic 1 DQ 2 Define clinical significance, and explain the difference between clinical and statistical significance

HRM 635 Topic 1 DQ 2 Define clinical significance and explain the difference between clinical and statistical significance

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Topic 1 DQ 2

Jun 6-10, 2022

Not all EBP projects result in statistically significant results. Define clinical significance, and explain the difference between clinical and statistical significance. How can you use clinical significance to support positive outcomes in your project?

Coraline Powell

Posted Date

Jun 10, 2022, 11:23 PM

Clinical significance is the significance that is linked to the significance of a course of treatments. When a project has clinical significance, it means that the intervention that was implemented had both genuine and quantifiable effects (Polit, 2017). Clinical significance has various key applications and it is mostly in major applications such as pharmaceutical testing and medical research or even in non-medical research, but it is also used in the critique of data sets.

On the other hand, statistical significance on the other hand is significance that emanates from the finding that an event is unlikely to have been caused by something else, or to have occurred by chance (Andrade, 2019).

During the implementation of EBP, I would use clinical significance to show the superiority of the interest, as compared to competing interventions. I would first design my intention in such a manner that it is extensively supported by evidence that has achieved both clinical and statistical significance, and also ensure that there are no outliers that ultimately affect the intervention. My intervention which is Nicotine Replacement Therapy and Education and in this case, I would use clinical

significance to prove that both of these intentions would have a more positive impact than no intervention at all.

References

Andrade C. (2019). The P Value and Statistical Significance: Misunderstandings, Explanations, Challenges, and Alternatives. Indian journal of psychological medicine, 41(3), 210–215. https://doi.org/10.4103/IJPSYM.IJPSYM_193_19

Polit D. F. (2017). Clinical significance in nursing research: A discussion and descriptive analysis. International journal of nursing studies, 73, 17–23. https://doi.org/10.1016/j.ijnurstu.2017.05.002

Lydia Kwofie

Posted Date

Jun 10, 2022, 10:55 PM

In a successful evidence-based project implementation, it is essential to understand and interpret the research findings. Therefore, it becomes critical to recognize and appreciate the difference between clinical significance and statistical significance. Statistical significance in research is phenomenon that is used to indicate the reliability of the study results by highlighting that a certain claim from data generated from experiment is attributed to a specific cause (Fleischmann & Vaughan, 2019). When the degree of statistical significance is high, the implication is that the observed relationship is unlikely coincidental but rather it has a direct association with a certain cause.

Clinical significance is essential in highlighting its implication in clinical practice. Clinically significant results or outcomes are subjective interpretations that are based on research findings as having healthcare implications for the specified patient. Clinically significant results indicate that the research findings can influence the healthcare practices and interventions hence shaping the behavior of healthcare practitioners. For results to be labeled clinically significant, the data must convince medical experts that the findings can inform the provision of care for a particular patient.

In the case of evidence-based research practice, it is essential to determine statistical significance of the research results before ascertaining whether the results are clinically significant. The main reason for establishing statistical significance before determining clinical significance is that clinical significance is determined after evaluating several research or experimental findings and confirming that they are statistically significant (Polit, 2017). I can make use of clinical significance to inform positive outcomes in my project outcome by ensuring that the results are statistically significant because clinical significance is informed by statistically significant results.

References

Fleischmann, M., & Vaughan, B. (2019). Commentary: statistical significance and clinical significance-a call to consider patient reported outcome measures, effect size, confidence interval and minimal clinically important difference (MCID). Journal of bodywork and movement therapies, 23(4), 690-694.

 

Polit, D. F. (2017). Clinical significance in nursing research: A discussion and descriptive analysis. International Journal of Nursing Studies, 73, 17-23.

 

 

 

 

Kitty Gay

Posted Date

Jun 10, 2022, 10:51 PM

Evidence-based practices (EBP) often have statistical information to assess or base project results and the clinical significance is key as it points to “patient safety or efficacy” and the true value of assessing via clinical research statistical results (Page, 2014). Page also informs us of the importance to incorporate information including effect sizes and confidence intervals for “clinically-relevant information” and ultimately the results are “only of value if it is properly interpreted” (2014). However, this is not the only venue to assess the outcome of a project.

Betterham and Watkins point out the statistical significance of there being or lacking differences is of limited value and stressing that a non-significant outcome does not necessarily (italics are Kitty’s) mean that a treatment or project was of no or minuscule value as many factors including sample size are key factors in the results (2006). Page continues with insight that a project or research not have an outcome that is clinically significant, yet is statistically significant “and vice-versa) (2014).

The site I am doing my preceptorship at has maintained records on each patient who has tested for Covid-19. The word has gotten out locally and beyond and in an interview, Dr. Tyson shared, their sites were seeing 200-400 persons a day (2021).  The patients they saw were provided interventions from the beginning; which we now know as Covid-19, which addressed patients symptoms including possible headache, body aches, nausea, vomiting, shortness of breath or difficulty breathing and/or temp. their test results, symptoms or asymptomatic, what interventions needed or prescribed, if additional indications led to chest x-ray and/or breathing treatment and ultimately regarding the follow-up call or return to office visit for assessment, further medications or the need to go to the hospital. In most of the cases, there has been clinical significance to optimal outcome and less need of admittance to the hospital.

Resources

Batterham, A.M. and Hopkins, W. G. (2006). Making meaningful inferences about magnitudes. International Journal of Sports Physiology Performance. (1), 50‐57.

Page, P. (2014). beyond statistical significance: clinical interpretation of rehabilitation research literature. International Journal of Sports Physical Therapy, 9(5): 726–736. Beyond statistical significance: clinical interpretation of rehabilitation research literature – PMC (nih.gov)

 

Tyson, B. (2021). The miracle of the Imperial Valley: Dr. Tyson’s first-person account of COVID-19. The Desert Review. https://www.thedesertreview.com/news/the-miracle-of-the-imperial-valley-dr-tyson-s-first-person-account-of-covid-19/article_a8707136-196b-11eb-bc7b-87d7730460bb.html

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Grading Rubric Guidelines

Performance Category	10	9	8	4	0
Scholarliness Demonstrates achievement of scholarly inquiry for professional and academic decisions.	Provides relevant evidence of scholarly inquiry clearly stating how the evidence informed or changed professional or academic decisions Evaluates literature resources to develop a comprehensive analysis or synthesis. Uses valid, relevant, and reliable outside sources to contribute to the threaded discussion	Provides relevant evidence of scholarly inquiry but does not clearly state how the evidence informed or changed professional or academic decisions. Evaluates information from source(s) to develop a coherent analysis or synthesis. Uses some valid, relevant, reliable outside sources to contribute to the threaded discussion.	Discusses using scholarly inquiry but does not state how scholarly inquiry informed or changed professional or academic decisions. Information is taken from source(s) with some interpretation/evaluation, but not enough to develop a coherent analysis or synthesis. Little valid, relevant, or reliable outside sources are used to contribute to the threaded discussion. Demonstrates little or no understanding of the topic.	Discusses using scholarly inquiry but does not state how scholarly inquiry informed or changed professional or academic decisions. Information is taken from source(s) without any interpretation/evaluation. The posting uses information that is not valid, relevant, or reliable	No evidence of the use of scholarly inquiry to inform or change professional or academic decisions. Information is not valid, relevant, or reliable
Performance Category	10	9	8	4	0
Application of Course Knowledge – Demonstrate the ability to analyze, synthesize, and/or apply principles and concepts learned in the course lesson and outside readings and relate them to real-life professional situations	Posts make direct reference to concepts discussed in the lesson or drawn from relevant outside sources; Applies concepts to personal experience in the professional setting and or relevant application to real life.	Posts make direct reference to concepts discussed in the lesson or drawn from relevant outside sources. Applies concepts to personal experience in their professional setting and or relevant application to real life Interactions with classmates are relevant to the discussion topic but do not make direct reference to lesson content	Posts are generally on topic but do not build knowledge by incorporating concepts and principles from the lesson. Does not attempt to apply lesson concepts to personal experience in their professional setting and or relevant application to real life Does not demonstrate a solid understanding of the principles and concepts presented in the lesson	Posts do not adequately address the question posed either by the discussion prompt or the instructor’s launch post. Posts are superficial and do not reflect an understanding of the lesson content Does not attempt to apply lesson concepts to personal experience in their professional setting and or relevant application to real life	Posts are not related to the topics provided by the discussion prompt or by the instructor; attempts by the instructor to redirect the student are ignored No discussion of lesson concepts to personal experience in the professional setting and or relevant application to real life
Performance Category	5	4	3	2	0
Interactive Dialogue Replies to each graded thread topic posted by the course instructor, by Wednesday, 11:59 p.m. MT, of each week, and posts a minimum of two times in each graded thread, on separate days. (5 points possible per graded thread)	Exceeds minimum post requirements Replies to each graded thread topic posted by the course instructor, by Wednesday, 11:59 p.m. MT, of each week, and posts three or more times in each graded thread, over three separate days. Replies to a post posed by faculty and to a peer Summarizes what was learned from the lesson, readings, and other student posts for the week.	Replies to each graded thread topic posted by the course instructor, by Wednesday, 11:59 p.m. MT, of each week, and posts a minimum of two times in each graded thread, on separate days Replies to a question posed by a peer Summarizes what was learned from the lesson, readings, and other student posts for the week.	Meets expectations of 2 posts on 2 different days. The main post is not made by the Wednesday deadline Does not reply to a question posed by a peer or faculty	Has only one post for the week Discussion posts contain few, if any, new ideas or applications; often are a rehashing or summary of other students’ comments	Does not post to the thread No connections are made to the topic
	Minus 1 Point	Minus 2 Point	Minus 3 Point	Minus 4 Point	Minus 5 Point
Grammar, Syntax, APA Note: if there are only a few errors in these criteria, please note this for the student in as an area for improvement. If the student does not make the needed corrections in upcoming weeks, then points should be deducted. Points deducted for improper grammar, syntax and APA style of writing. The source of information is the APA Manual 6th Edition	2-3 errors in APA format. Written responses have 2-3 grammatical, spelling, and punctuation errors. Writing style is generally clear, focused, and facilitates communication.	4-5 errors in APA format. Writing responses have 4-5 grammatical, spelling and punctuation errors. Writing style is somewhat focused.	6-7 errors in APA format. Writing responses have 6-7 grammatical, spelling and punctuation errors. Writing style is slightly focused making discussion difficult to understand.	8-10 errors in APA format. Writing responses have 8-10 grammatical, spelling and punctuation errors. Writing style is not focused, making discussion difficult to understand.	Post contains greater than 10 errors in APA format. Written responses have more than 10 grammatical, spelling and punctuation errors. Writing style does not facilitate communication. The student continues to make repeated mistakes in any of the above areas after written correction by the instructor
	0 points lost				-5 points lost
Total Participation Requirements per discussion thread	The student answers the threaded discussion question or topic on one day and posts a second response on another day.				The student does not meet the minimum requirement of two postings on two different days
Early Participation Requirement per discussion thread	The student must provide a substantive answer to the graded discussion question(s) or topic(s), posted by the course instructor (not a response to a peer), by Wednesday, 11:59 p.m. MT of each week.				The student does not meet the requirement of a substantive response to the stated question or topic by Wednesday at 11:59 pm MT.

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