NUR-550 Topic 1 DQ 1 Identify the different levels of translational research<\/h3>\n
Click here to ORDER an A++ paper from our Verified MASTERS and DOCTORATE WRITERS: NUR-550 Topic 1 DQ 1 Identify the different levels of translational research<\/strong><\/a>\u00a0<\/span><\/p>\n Nov 24-26, 2022<\/p>\n Identify the different levels of translational research<\/a>. Explain how translational research is different from evidence-based practice and discuss application to population health management.<\/p>\n REPLY TO DISCUSSION<\/p>\n Heather Kennedy<\/p>\n Nov 25, 2022, 9:15 AM<\/p>\n Topic 1 Classroom Assessment Technique (CAT):<\/p>\n <\/p>\n Optional assignment for participation credit.<\/p>\n <\/p>\n Please complete the memory matrix in the attached document and post as a reply.<\/p>\n <\/p>\n According to Titler (2018), translational research is a fluid process from basic research then implementing in clinical practice through public health to enhance health and its outcomes. Please complete the table (Rows 1-4) to indicate how Translation Research progresses across five phases:<\/p>\n <\/p>\n Titler, M. G. (2018). Translation Research in Practice: An Introduction.\u202fOnline Journal of Issues in Nursing<\/em>,\u202f23<\/em>(2), 1. https:\/\/doi-org.lopes.idm.oclc.org\/10.3912\/OJIN.Vol23No02Man01<\/p>\n Attachments<\/p>\n CAT1.docx<\/a><\/p>\n REPLY<\/p>\n Nov 25, 2022, 10:33 AM<\/p>\n According to Titler (2018), translational research is a fluid process from basic research then implementing in clinical practice through public health to enhance health and its outcomes. Please complete the table (Rows 1-4) to indicate how Translation Research progresses across five phases:<\/p>\n T0\/Basic Science Research<\/p>\n <\/p>\n T1\/Testing efficacy and safety with small group of humans<\/p>\n Proof of concept\/ Phase 1 clinical trials<\/p>\n <\/p>\n T3\/ 2.\u00a0Testing the efficacy and safety with larger group of humans; compare to common treatments<\/em><\/strong><\/p>\n Phase 2 and Phase 3 clinical trials<\/p>\n <\/p>\n T4\/Translation to Practice<\/p>\n <\/p>\n Phase 5 Population-level outcomes research<\/p>\n References<\/p>\n Titler, M. G. (2018). Translation Research in Practice: An Introduction.\u00a0Online Journal of Issues in Nursing<\/em>,\u00a023<\/em>(2), 1. https:\/\/doi-org.lopes.idm.oclc.org\/10.3912\/OJIN.Vol23No02Man01<\/p>\n REPLY<\/p>\n Nov 25, 2022, 3:27 PM<\/p>\n Attached is my completed memory matrix.<\/p>\n Attachments<\/p>\n SF-CAT1.docx<\/a><\/p>\n REPLY<\/p>\n Nov 28, 2022, 6:54 PM<\/p>\n T0\/Basic Science Research\u00e01. Preclinical and animal studies<\/p>\n T1\/Testing efficacy and safety with a small group of humans\u00e0Proof of concept\/ Phase 1 clinical trials<\/p>\n T3\/ Translation to patients \u00e02. Phase 2 and Phase 3 clinical trials<\/p>\n T4\/Translation to practice\u00e03. Phase 4 clinical trials and clinical outcomes research<\/p>\n T5\/ 4. Transition to community\u00e0Phase 5 Population-level outcomes research<\/p>\n <\/p>\n <\/p>\n What is Translational Research?<\/em>\u00a0(n.d.-b). Translational Research Institute. https:\/\/tri.uams.edu\/about-tri\/what-is-translational-research\/<\/p>\n REPLY<\/p>\n Nov 29, 2022, 12:21 PM<\/p>\n T0\/ Basic Science Research:\u00a01 Preclinical and animal studies<\/strong><\/p>\n <\/p>\n T1\/ Testing efficacy and safety with small group of humans: Proof of concept\/Phase 1 Clinical trials<\/p>\n <\/p>\n T3\/2\u00a0Testing the efficacy and safety with larger group of humans; compare to common treatments<\/strong>: Phase 2 and Phase 3 Clinical trials<\/p>\n <\/p>\n T4\/ Translation to Practice:\u00a03 Clinical trials and clinical outcomes research.<\/strong><\/p>\n <\/p>\n T5\/4 Translation to Community:\u00a0<\/strong>Phase 5 Population- level outcome research<\/p>\n <\/p>\n References<\/p>\n Titler, M. G. (2018). Translation Research in Practice: An Introduction.\u00a0Online Journal of Issues in Nursing<\/em>,\u00a023<\/em>(2), 1. https:\/\/doi-org.lopes.idm.oclc.org\/10.3912\/OJIN.Vol23No02Man01<\/p>\n <\/p>\n REPLY<\/p>\n Nov 30, 2022, 6:35 PM<\/p>\n Attachments<\/p>\n REPLY<\/p>\n Nov 27, 2022, 12:06 PM(edited)<\/p>\n Translational research appears to be a tool used to close the gap between evidence-base practice and the clinical delivery of direct nursing care. It is described as a way to improve population health and the delivery system. Translational science looks for ways to implement evidence based practice, so being something entirely different than EBP, it works hand in hand with EBP to improve patient outcomes. Translational research digs in to make a clear understanding of what implementation strategies work, the people they work for and answers the question of why. This body of knowledge, translation science, provides a base for guiding the selection of implementation strategies. (Titler, 2018) The are levels of translational research, T1 developing treatments and interventions, T2 testing the effectiveness of those treatments and interventions and T3 is dissemination and implementation for change. In addition another resource describes 5 phases beginning with T0 through T5. T0 starts with basic research, preclinical. T1 is testing on a small group of humans, T2 and T3 are more trials on an even larger group of humans. T4 is the outcome research \/ translation to practice and lastly T5 goes out to the population or translation to the community. This type of research seems more hands on and creates positive outcomes to the patients who are in need of direct and immediate care.<\/p>\n <\/p>\n Titler, M.G., (2018). Translation Research in Practice: An Introduction.\u00a0OJIN: The Online Journal of Issues in Nursing\u00a023<\/em>(2). https:\/\/doi.org\/10.3912\/OJIN.Vol23No02Man01<\/a><\/p>\n <\/p>\n Translational research \u2013 defining the “T’s”<\/em>. Translational Research \u2013 Defining the “T’s” | Translational Cancer Research Network. (n.d.). Retrieved November 27, 2022, from http:\/\/www.tcrn.unsw.edu.au\/translational-research-<\/a>definitions#:~:text=Translational%20Pipeline&text=The%20schematic%20outlines%2Fclassifies%20the%20stages%20of%20translational%20research%20as%3A&text=T1%20%2D%20developing%20treatments%20and%20interventions.&text=T2%20%2D%20testing%20the%20efficacy%20and%20effectiveness%20of%20these%20treatments%20and%20interventions.&text=T3%20%2D%20dissemination%20and%20implementation%20research%20for%20system%2Dwide%20change.<\/p>\n REPLY<\/p>\n Nov 27, 2022, 8:01 PM<\/p>\n <\/p>\n I agree that translational research does come across as more hands on than traditional research. The focus of translational research incorporates\u00a0humans into the research process as soon as possible with the goal of incorporating concepts that have been proven to be beneficial into practice quickly. (Titler, 2018) Titler (2018) also points out that translational research is still in the development stage<\/p>\n and the specific terminology and definitions for the\u00a0concept have not been agreed upon yet. While researching translational research, some sites state that the concept has four phases while others mention five. Hopefully, this ambiguity of terminology will be cleared up within the healthcare industry soon.<\/p>\n <\/p>\n Titler, M.G., (2018). Translation Research in Practice: An Introduction.\u00a0OJIN: The Online Journal of Issues in Nursing\u00a023<\/em>(2). https:\/\/doi.org\/10.3912\/OJIN.Vol23No02Man01<\/a><\/p>\nTopic 1 DQ 1<\/strong><\/h2>\n
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Reference:NUR-550 Topic 1 DQ 1 Identify the different levels of translational research<\/h3>\n