Sample Answer for NURS 6521 Week 11: Pediatrics Included After Question<\/strong><\/em><\/h2>\nThe unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable since very few drugs have been specifically researched and tested with children.<\/span>\u00a0<\/span><\/p>\nWhen treating children, prescribers often adjust dosages approved for adults to accommodate a child\u2019s weight. However, children are not just \u201csmaller\u201d adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism<\/a>, and excretion. Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.<\/span>\u00a0<\/span><\/p>\nTo prepare:<\/span><\/b>\u00a0<\/span><\/h2>\n\n- Review the Panther et al (2017) and Corney, Lebel, Bailey, and Bussieres (2015) articles in the Learning Resources. Reflect on situations in which children should be prescribed drugs for off-label use.<\/span>\u00a0<\/span><\/li>\n
- Think about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
With these thoughts in mind:<\/span>\u00a0<\/span><\/p>\nBy Day 3<\/span><\/b>\u00a0<\/span><\/h2>\nPost<\/span><\/b> an explanation of circumstances under which children should be prescribed drugs for off-label use. Then, describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.<\/span>\u00a0<\/span><\/p>\nBy Day 6<\/span><\/b>\u00a0<\/span><\/h2>\nRead<\/span><\/b> a selection of your colleagues\u2019 responses and <\/span>respond <\/span><\/b>to <\/span>at least two<\/span><\/b> of your colleagues on <\/span>two different days<\/span><\/b> who provided a different rationale than you did, in one or more of the following ways:<\/span>\u00a0<\/span><\/p>\n\n- Offer and support an alternative perspective using readings from the classroom or from your own research in the Walden Library.<\/span>\u00a0<\/span><\/li>\n
- Validate an idea with your own experience and additional research.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
Note:<\/span><\/b> For this Discussion, you are required to complete your initial post before you will be able to view and respond to your colleagues\u2019 postings. Begin by clicking on the \u201cPost to Discussion Question\u201d link and then select \u201cCreate Thread\u201d to complete your initial post. Remember, once you click on Submit, you cannot delete or edit your own posts, and you cannot post anonymously. Please check your post carefully before clicking on <\/span>Submit!<\/span><\/b>\u00a0<\/span><\/p>\nChildren deal with variety of health issues similar to adults, but they also have issues that are more prevalent within their population. One issue that significantly impacts children is the prescription of drugs for off-label use. Consider the case of Rebecca Riley. When she was two years old, Riley was diagnosed with ADHD, and by age three, she was diagnosed with bipolar disorder. In the span of two years, Riley\u2019s doctor prescribed four drugs off-label: Clonidine, Depakote, Zyprexa, and Seroquel. Riley\u2019s doctor also approved 13 increases in drug dosages. Then, at age four, Riley died from pneumonia combined with a toxic level of prescription drugs (Lambert, 2010). Cases such as this have brought attention to the off-label use of drugs in pediatric patients, as well as the importance of monitoring patient reactions to prescribed drugs and evaluating the effects of drug-drug interactions. As an advanced practice nurse, how do you determine the appropriate use of off-label drugs in pediatrics? Are there certain drugs that should be avoided with pediatric patients?<\/span><\/p>\nThis week you examine the practice of prescribing off-label drugs to children. You also explore strategies for making off-label drug use safer for children from infancy to adolescence as it is essential that you are prepared to make drug\u2013related decisions for pediatric patients in clinical settings.<\/span>\u00a0<\/span><\/p>\nLearning Objectives<\/span><\/b>\u00a0<\/span><\/h2>\nBy the end of this week, students will:<\/span><\/b>\u00a0<\/span><\/p>\n\n- Evaluate the practice of prescribing off-label drugs to children<\/span>\u00a0<\/span><\/li>\n
- Analyze strategies to make the off-label use of drugs safer for children<\/span>\u00a0<\/span><\/li>\n
- Understand and apply key terms, concepts, and principles related to prescribing drugs to treat pediatric patients<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
Photo Credit: XiXinXing\/Getty Images<\/span>\u00a0<\/span><\/p>\n![\"NURS](\"http:\/\/nursingassignmentcrackers.com\/wp-content\/uploads\/2024\/02\/Capture-3-6-300x91.png\")
NURS 6521 Week 11: Pediatrics<\/figcaption><\/figure>\nLearning Resources<\/span><\/b>\u00a0<\/span><\/h2>\nNote:<\/span><\/b> To access this week\u2019s required library resources, please click on the link to the Course Readings List, found in the <\/span>Course Materials<\/span><\/b> section of your Syllabus.<\/span>\u00a0<\/span><\/p>\nThis page contains the Learning Resources for this week. Be sure to scroll down the page to see all of this week’s assigned Learning Resources. To access select media resources, please use the media player below.<\/span>\u00a0<\/span><\/p>\nA Sample Answer For the Assignment: NURS 6521 Week 11: Pediatrics<\/strong><\/h2>\nTitle: NURS 6521 Week 11: Pediatrics<\/strong><\/h2>\nMedications are frequently used for reasons other than what they are prescribed for.\u202f\u202fWhen this occurs, it called off label use, and the reason the medication is used is not listed on the medication insert.\u202f\u202fUsing a medication that off-label does not mean that it is not proper for the child, off-label does not mean improper, illegal, contraindicated, or investigational use (American Academy of Pediatrics, 2014, p. 563).\u202f\u202fWhen using medications for the off-label reason, the child has to be monitored closely.\u202f\u202f<\/span>\u00a0<\/span><\/p>\nCircumstance<\/span><\/b>\u00a0<\/span><\/h2>\n\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202fThere are not many clinical trials if that use children as participants, so results are not clear.\u202f\u202fHowever, just because there is limited prescribing guidance does not mean that the FDA does not allow prescribing these medications in children (Children Hospital, 2018).\u202f\u202fWhat is most feared about prescribing off-label drugs is the fear of harming the child. In certain circumstances when there are no recommended medications in the pediatric form for certain medical issues, the provider has to turn to off-label drugs.\u202f\u202fThe use of these medications is usually determined by a clinician with a season experienced history among pediatrics (Kimland, 2014).\u202f\u202fChildren are not little adults in addition to being small their bodies metabolize drugs differently than adults.\u202f\u202fIt is appropriate to use off label prescribing when the treatment is a benefit to the patient (Pediatrics, 2014).\u202f\u202fIf the benefit outweighs, the risk off-labeling may be the best choice.\u202f\u202fEven though the passage of the Best Pharmaceuticals for Children Act and Pediatric Research Act and Equity Act has caused improvement in rational prescribing for children including more than 500 labeling changes off-label use is still a problem for infants, children, and adolescents because of a large number of drugs still have no information in the labeling for use in pediatrics (Pediatrics, 2014).\u202f\u202f<\/span>\u00a0<\/span><\/p>\nStrategies To Make Safer<\/span><\/b>\u00a0<\/span><\/h2>\n\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202fA strategy for increasing safety in medication prescribing would be to conduct clinical trials to track the effects on children.\u202f\u202fThe off-label use of drugs should be done in good faith, in the best interest of the patient to conform to accepted professional standards (American Academy of Pediatrics, 2014, p. 565).\u202f\u202fWhen prescriber the provider should ensure that the benefit outweighs the risk.\u202fAlso, the patient and guardian should be informed with all possible risk and side effects before treatment.\u202f\u202f<\/span>\u00a0<\/span><\/p>\nReference:<\/span>\u00a0<\/span><\/h2>\nDrugs, C. O. (2014, March 01). Off-Label Use of Drugs in Children. Retrieved February 6, 2019,\u202f<\/span>\u00a0<\/span><\/p>\nfrom http:\/\/pediatrics.aappublications.org\/content\/133\/3\/563<\/a><\/span>\u00a0<\/span><\/p>\n\n- Kimland\u202f(2014)\u202fOff-label and unlicensed drug use in children,\u202fPaediatrics and International\u202f<\/span><\/li>\n<\/ol>\n
Child Health,\u202f34:1,\u202f1-2,\u202fDOI:\u202f<\/span>10.1179\/2046905513<\/span><\/a>\u00a0<\/span><\/p>\n
When treating children, prescribers often adjust dosages approved for adults to accommodate a child\u2019s weight. However, children are not just \u201csmaller\u201d adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism<\/a>, and excretion. Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.<\/span>\u00a0<\/span><\/p>\n With these thoughts in mind:<\/span>\u00a0<\/span><\/p>\n Post<\/span><\/b> an explanation of circumstances under which children should be prescribed drugs for off-label use. Then, describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.<\/span>\u00a0<\/span><\/p>\n Read<\/span><\/b> a selection of your colleagues\u2019 responses and <\/span>respond <\/span><\/b>to <\/span>at least two<\/span><\/b> of your colleagues on <\/span>two different days<\/span><\/b> who provided a different rationale than you did, in one or more of the following ways:<\/span>\u00a0<\/span><\/p>\n Note:<\/span><\/b> For this Discussion, you are required to complete your initial post before you will be able to view and respond to your colleagues\u2019 postings. Begin by clicking on the \u201cPost to Discussion Question\u201d link and then select \u201cCreate Thread\u201d to complete your initial post. Remember, once you click on Submit, you cannot delete or edit your own posts, and you cannot post anonymously. Please check your post carefully before clicking on <\/span>Submit!<\/span><\/b>\u00a0<\/span><\/p>\n Children deal with variety of health issues similar to adults, but they also have issues that are more prevalent within their population. One issue that significantly impacts children is the prescription of drugs for off-label use. Consider the case of Rebecca Riley. When she was two years old, Riley was diagnosed with ADHD, and by age three, she was diagnosed with bipolar disorder. In the span of two years, Riley\u2019s doctor prescribed four drugs off-label: Clonidine, Depakote, Zyprexa, and Seroquel. Riley\u2019s doctor also approved 13 increases in drug dosages. Then, at age four, Riley died from pneumonia combined with a toxic level of prescription drugs (Lambert, 2010). Cases such as this have brought attention to the off-label use of drugs in pediatric patients, as well as the importance of monitoring patient reactions to prescribed drugs and evaluating the effects of drug-drug interactions. As an advanced practice nurse, how do you determine the appropriate use of off-label drugs in pediatrics? Are there certain drugs that should be avoided with pediatric patients?<\/span><\/p>\n This week you examine the practice of prescribing off-label drugs to children. You also explore strategies for making off-label drug use safer for children from infancy to adolescence as it is essential that you are prepared to make drug\u2013related decisions for pediatric patients in clinical settings.<\/span>\u00a0<\/span><\/p>\n By the end of this week, students will:<\/span><\/b>\u00a0<\/span><\/p>\n Photo Credit: XiXinXing\/Getty Images<\/span>\u00a0<\/span><\/p>\n Note:<\/span><\/b> To access this week\u2019s required library resources, please click on the link to the Course Readings List, found in the <\/span>Course Materials<\/span><\/b> section of your Syllabus.<\/span>\u00a0<\/span><\/p>\n This page contains the Learning Resources for this week. Be sure to scroll down the page to see all of this week’s assigned Learning Resources. To access select media resources, please use the media player below.<\/span>\u00a0<\/span><\/p>\n Medications are frequently used for reasons other than what they are prescribed for.\u202f\u202fWhen this occurs, it called off label use, and the reason the medication is used is not listed on the medication insert.\u202f\u202fUsing a medication that off-label does not mean that it is not proper for the child, off-label does not mean improper, illegal, contraindicated, or investigational use (American Academy of Pediatrics, 2014, p. 563).\u202f\u202fWhen using medications for the off-label reason, the child has to be monitored closely.\u202f\u202f<\/span>\u00a0<\/span><\/p>\n \u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202fThere are not many clinical trials if that use children as participants, so results are not clear.\u202f\u202fHowever, just because there is limited prescribing guidance does not mean that the FDA does not allow prescribing these medications in children (Children Hospital, 2018).\u202f\u202fWhat is most feared about prescribing off-label drugs is the fear of harming the child. In certain circumstances when there are no recommended medications in the pediatric form for certain medical issues, the provider has to turn to off-label drugs.\u202f\u202fThe use of these medications is usually determined by a clinician with a season experienced history among pediatrics (Kimland, 2014).\u202f\u202fChildren are not little adults in addition to being small their bodies metabolize drugs differently than adults.\u202f\u202fIt is appropriate to use off label prescribing when the treatment is a benefit to the patient (Pediatrics, 2014).\u202f\u202fIf the benefit outweighs, the risk off-labeling may be the best choice.\u202f\u202fEven though the passage of the Best Pharmaceuticals for Children Act and Pediatric Research Act and Equity Act has caused improvement in rational prescribing for children including more than 500 labeling changes off-label use is still a problem for infants, children, and adolescents because of a large number of drugs still have no information in the labeling for use in pediatrics (Pediatrics, 2014).\u202f\u202f<\/span>\u00a0<\/span><\/p>\n \u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202f\u202fA strategy for increasing safety in medication prescribing would be to conduct clinical trials to track the effects on children.\u202f\u202fThe off-label use of drugs should be done in good faith, in the best interest of the patient to conform to accepted professional standards (American Academy of Pediatrics, 2014, p. 565).\u202f\u202fWhen prescriber the provider should ensure that the benefit outweighs the risk.\u202fAlso, the patient and guardian should be informed with all possible risk and side effects before treatment.\u202f\u202f<\/span>\u00a0<\/span><\/p>\n Drugs, C. O. (2014, March 01). Off-Label Use of Drugs in Children. Retrieved February 6, 2019,\u202f<\/span>\u00a0<\/span><\/p>\n from http:\/\/pediatrics.aappublications.org\/content\/133\/3\/563<\/a><\/span>\u00a0<\/span><\/p>\n Child Health,\u202f34:1,\u202f1-2,\u202fDOI:\u202f<\/span>10.1179\/2046905513<\/span><\/a>\u00a0<\/span><\/p>\nTo prepare:<\/span><\/b>\u00a0<\/span><\/h2>\n
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By Day 3<\/span><\/b>\u00a0<\/span><\/h2>\n
By Day 6<\/span><\/b>\u00a0<\/span><\/h2>\n
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Learning Objectives<\/span><\/b>\u00a0<\/span><\/h2>\n
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Learning Resources<\/span><\/b>\u00a0<\/span><\/h2>\n
A Sample Answer For the Assignment: NURS 6521 Week 11: Pediatrics<\/strong><\/h2>\n
Title: NURS 6521 Week 11: Pediatrics<\/strong><\/h2>\n
Circumstance<\/span><\/b>\u00a0<\/span><\/h2>\n
Strategies To Make Safer<\/span><\/b>\u00a0<\/span><\/h2>\n
Reference:<\/span>\u00a0<\/span><\/h2>\n
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