In this exercise, you will complete a 5-essay type question Knowledge Check to gauge your understanding of this module\u2019s content. \u202f<\/span>\u00a0<\/span><\/p>\n Possible topics covered in this Knowledge Check include:<\/span>\u00a0<\/span><\/p>\n Three basic bone-formations:<\/span>\u00a0<\/span><\/p>\n Be sure to review the Learning Resources before completing this activity.<\/span> Complete\u202f<\/span><\/b>the Knowledge Check\u202fby Day 7 of Week 7.<\/span>\u00a0<\/span><\/p>\n <\/p>\n This quiz was locked Apr 16 at 10:59pm.<\/span>\u00a0<\/span><\/p>\n Attempt History<\/span>\u00a0<\/span><\/p>\n Score for this quiz:\u202f<\/span>17.8<\/span><\/b>\u202fout of 20<\/span>\u00a0<\/span><\/p>\n Submitted Apr 16 at 10:10am<\/span>\u00a0<\/span><\/p>\n This attempt took 6,114 minutes.<\/span>\u00a0<\/span><\/p>\n \u202f<\/span><\/p>\n A\u202f68-year-old\u202fobese male presents to the clinic with a\u202f3-day\u202fhistory of fever with chills, and\u202fLt. great toe pain that has gotten progressively worse. Patient states this is the first time that this has\u202fhappened,\u202fand nothing has made it better and walking on\u202fhis right foot makes it worse.\u202fHe has tried\u202facetaminophen,\u202fbut it did not help. He\u202ftook several ibuprofen\u202ftablets\u202flast night which did give him a bit of relief.\u202f<\/span>\u00a0<\/span><\/p>\n HPI: hypertension treated with Lisinopril\/HCTZ\u202f.<\/span>\u00a0<\/span><\/p>\n SH: Denies smoking. Drinking: \u201ca fair amount of red wine\u201d every week.\u202fGeneral appearance: Ill appearing male\u202fwho sits with\u202fhis\u202fright foot elevated.\u202f<\/span>\u00a0<\/span><\/p>\n PE: \u202fremarkable for a temp of 100.2, pulse 106, respirations\u202f20 and BP 158\/92. Right great toe (first\u202fmetatarsal\u202fphalangeal [MTP])\u202fnoticeably swollen and red. Unable to palpate to assess range of motion due to extreme pain.\u202fCBC\u202fand\u202fComplete metabolic profile revealed\u202fWBC 15,000 mm<\/span>3<\/span>\u202fand\u202furic acid 9.0 mg\/dl.<\/span>\u00a0<\/span><\/p>\n Diagnoses the patient with acute gout.<\/span>\u00a0<\/span><\/p>\n Explain the pathophysiology of gout.<\/span><\/i>\u00a0<\/span><\/p>\n \u00a0<\/span><\/p>\n Your Answer:<\/span>\u00a0<\/span><\/p>\n Gout is caused by disorders of purine metabolism, increased uric acid production, and reduced uric acid excretion, causing increased serum uric acid (sUA) levels. This forms monosodium urate (MSU) crystals deposited in the joints, kidneys, and other tissues. Gout occurs following the precipitation of monosodium urate crystals in a joint space (Clebak et al., 2020). The deposition of the urate crystals elicits activation of the immune system, causing the release of various inflammatory cytokines and the recruitment of neutrophils. Over time, the joint space becomes irreversibly damaged, causing chronic pain and disability with grossly deformed joints. Tophi may also form at the joint space. These are subcutaneous nodules containing monosodium urate crystals in a matrix of lipids, proteins, and mucopolysaccharides (Clebak et al., 2020). The first metatarsophalangeal joint is mostly affected.<\/span>\u00a0<\/span><\/p>\n \u202f<\/span>\u00a0<\/span><\/p>\n Clebak, K. T., Morrison, A., & Croad, J. R. (2020). Gout: Rapid evidence review.\u202f<\/span>American family physician<\/span><\/i>,\u202f<\/span>102<\/span><\/i>(9), 533-538.<\/span>\u00a0<\/span><\/p>\n \u00a0<\/span>A\u202f68-year-old\u202fobese male presents to the clinic with a\u202f3-day\u202fhistory of fever with chills, and\u202fLt. great toe pain that has gotten progressively worse. Patient states this is the first time that this has\u202fhappened,\u202fand nothing has made it better and walking on\u202fhis right foot makes it worse.\u202fHe has tried\u202facetaminophen,\u202fbut it did not help. He\u202ftook several ibuprofen\u202ftablets\u202flast night which did give him a bit of relief.\u202f<\/span>\u00a0<\/span><\/p>\n HPI: hypertension treated with Lisinopril\/HCTZ\u202f.<\/span>\u00a0<\/span><\/p>\n SH: Denies smoking. Drinking: \u201ca fair amount of red wine\u201d every week.\u202fGeneral appearance: Ill appearing male\u202fwho sits with\u202fhis\u202fright foot elevated.\u202f<\/span>\u00a0<\/span><\/p>\n PE: \u202fremarkable for a temp of 100.2, pulse 106, respirations\u202f20 and BP 158\/92. Right great toe (first\u202fmetatarsal\u202fphalangeal [MTP])\u202fnoticeably swollen and red. Unable to palpate to assess range of motion due to extreme pain.\u202fCBC\u202fand\u202fComplete metabolic profile revealed\u202fWBC 15,000 mm<\/span>3<\/span>\u202fand\u202furic acid 9.0 mg\/dl.<\/span>\u00a0<\/span><\/p>\n Diagnoses the patient with acute gout.<\/span>\u00a0<\/span><\/p>\n Explain why a patient with gout is more likely to develop renal calculi.<\/span>\u00a0<\/span><\/p>\n Your Answer:<\/span>\u00a0<\/span><\/p>\n Gout patients commonly present with nephrolithiasis. The development of renal calculi in patients with gout is primarily related to high levels of uric acid. The ionized forms of uric acid form salts like monosodium urate, disodium urate, or potassium urate (Bardin et al., 2021). Sodium is the main cation in the extracellular fluid. Urine acidifies along the renal tubules, causing a portion of urate to convert to uric acid. The solubility of uric acid in an aqueous solution is lesser than that of urate, but the saturation increases markedly with the increase in the pH value of urine (Bardin et al., 2021). Gout patients with long-term high uric acid levels have increased urinary uric acid concentration and form crystals after surpassing the solubility, which gradually enlarges to shape calculus.<\/span>\u00a0<\/span><\/p>\n \u202f<\/span><\/b>\u00a0<\/span><\/p>\n Bardin, T., Nguyen, Q. D., Tran, K. M., Le, N. H., Do, M. D., Richette, P., Letavernier, E., Correas, J. M., & Resche-Rigon, M. (2021). A cross-sectional study of 502 patients found a diffuse hyperechoic kidney medulla pattern in patients with severe gout.\u202f<\/span>Kidney international<\/span><\/i>,\u202f<\/span>99<\/span><\/i>(1), 218\u2013226. https:\/\/doi.org\/10.1016\/j.kint.2020.08.024<\/a><\/span>\u00a0<\/span><\/p>\n\n
\n
\n
RESOURCES<\/span>\u00a0<\/span><\/h2>\n
![\"NURS](\"http:\/\/nursingassignmentcrackers.com\/wp-content\/uploads\/2024\/01\/Capture-4-7-300x102.png\")
\nClick the weekly resources link to access the resources.\u202f<\/span>\u00a0<\/span><\/p>\nWEEKLY RESOURCES<\/span><\/b><\/a>\u00a0<\/span><\/h2>\n
BY DAY 7 OF WEEK 7<\/span>\u00a0<\/span><\/h3>\n
\n\n
\n \u00a0<\/span><\/td>\n Attempt<\/span><\/b>\u00a0<\/span><\/td>\n Time<\/span><\/b>\u00a0<\/span><\/td>\n Score<\/span><\/b>\u00a0<\/span><\/td>\n<\/tr>\n \n LATEST<\/span><\/b>\u00a0<\/span><\/td>\n Attempt 1<\/span><\/a>\u00a0<\/span><\/td>\n 6,114 minutes<\/span>\u00a0<\/span><\/td>\n 17.8 out of 20<\/span>\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n A Sample Answer For the Assignment: NURS 6501 NEUROLOGICAL AND MUSCULOSKELETAL DISORDERS<\/strong><\/h2>\n
Title: NURS 6501 NEUROLOGICAL AND MUSCULOSKELETAL DISORDERS<\/strong><\/h2>\n
Scenario 1: Gout<\/span><\/i><\/b>\u00a0<\/span><\/h3>\n
Question:<\/span><\/b>\u00a0<\/span><\/h2>\n
Reference<\/span><\/b>\u00a0<\/span><\/h2>\n
A Sample Answer 2 For the Assignment: NURS 6501 NEUROLOGICAL AND MUSCULOSKELETAL DISORDERS<\/strong><\/h2>\n
Title: NURS 6501 NEUROLOGICAL AND MUSCULOSKELETAL DISORDERS<\/strong><\/h2>\n
Scenario 1: Gout<\/span><\/i><\/b>\u00a0<\/span><\/h3>\n
Question:<\/span><\/b>\u00a0<\/span><\/h2>\n
\u202f<\/span><\/b>References<\/span><\/b>\u00a0<\/span><\/h2>\n