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NURS 6512 Discussion Week 2: Cardiovascular System

Alterations of the cardiovascular system can cause serious adverse events and may lead to death
when not treated in a timely and safe manner. Unfortunately, many patients with cardiovascular
disorders are unaware until complications appear. In clinical settings, patients often present with
symptoms of several cardiovascular disorders, making it essential for you, as the advanced
practice nurse, to be able to recognize these symptoms and recommend appropriate drug
treatment options.
This week, you examine the impact of patient factors that may lead to changes in
pharmacokinetic and pharmacodynamic processes on patient drug therapy for cardiovascular
disorders. You also explore ways to improve drug therapy plans for cardiovascular disorders
based on patient factors and overall health needs.
Learning Objectives
Students will:
 Analyze the influence of patient factors on pharmacokinetic and pharmacodynamic
 Analyze the impact of changes in pharmacokinetic and pharmacodynamic processes on
patient drug therapies
 Evaluate drug therapy plans for cardiovascular disorders

Learning Resources

Required Readings (click to expand/reduce)

Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for
advanced practice nurses and physician assistants (2 nd ed.) St. Louis, MO:
 Chapter 33, “Review of Hemodynamics” (pp. 285–289)
 Chapter 37, “Diuretics” (pp. 290–296)
 Chapter 38, “Drugs Acting on the Renin-Angiotensin-Aldosterone
System” (pp. 297–307)
 Chapter 39, “Calcium Channel Blockers” (pp. 308–312)
 Chapter 40, “Vasodilators” (pp. 313–317)

 Chapter 41, “Drugs for Hypertension” (pp. 316–324)
 Chapter 42, “Drugs for Heart Failure” (pp. 325–336)
 Chapter 43, “Antidysrhythmic Drugs” (pp. 337–348)
 Chapter 44, “Prophylaxis of Atherosclerotic Cardiovascular Disease:
Drugs That Help Normalize Cholesterol and Triglyceride Levels” (pp.
 Chapter 45, “Drugs for Angina Pectoris” (pp. 364–371)
 Chapter 46, “Anticoagulant and Antiplatelet Drugs” (pp. 372–388)

Required Media (click to expand/reduce)

Cardiovascular Disorders

Meet Dr. Norbert Myslinski as he discusses ACE inhibitors, angiotensin
inhibitors, beta-blockers, calcium channel blockers, and diuretics as different
categories of hypertension drugs. What potential drugs might be best
recommended for patients suffering from hypertension? (8m)

Walden University. (n.d.). Instructor feedback. https://cdn-

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