NURS 550 Discussion Levels of Translational Research

NURS 550 Discussion Levels of Translational Research

Sample Answer for NURS 550 Discussion Levels of Translational Research Included After Question


Identify the different levels of translational research. Explain how translational research is different from evidence-based practice and discuss application to population health management.

A Sample Answer For the Assignment: NURS 550 Discussion Levels of Translational Research

Title:  NURS 550 Discussion Levels of Translational Research

Translational research is form of clinical research that was first seen around 1993 (Rubio et al, 2010). So as far as research goes this is a fairly new was to look into things. There is also no clear definition of translational research, but essentially it encompasses two areas of translation one being the information obtained in pre-clinical studies, lab research and the other being the adaptation of best practices in the community with their cost effectiveness (Rubio et al, 2010). There are three levels of translational research, starting with T1, which involves the beginning research or development of an intervention, including the lab research, observational research and phase I and II clinical trials (Translational Research, n.d.). The second level is T2 the translation to patients, testing these interventions and their efficacy on the patient populace, including phase III clinical trials, studying how these new interventions work with disease processes and creating new guidelines with up-to-date information (Translational Research, n.d.). The third level is T3 disseminating and implementation of all the research into daily practice, creating the research evidence found into evidence-based practices across the profession (Translational Research, n.d.).

From this information there isn’t a difference between evidence-based practice and translational research, it is just a way to get to evidence based practice. By following the ‘three T’s’, the final step is to put all of this research into practice, as evidence-based practice. For public health this means the most up to date care and information as the natural progression of translational practice ends with practice. If there is no research being done in the area however, this has a negative impact on the population, as there is not up to date EPB related to that disease process and/or its co morbidities.

Rubio, D. M., Schoenbaum, E. E., Lee, L. S., Schteingart, D. E., Marantz, P. R., Anderson, K. E., Platt, L. D., Baez, A., & Esposito, K. (2010). Defining translational research: implications for training. Academic medicine : journal of the Association of American Medical Colleges85(3), 470–475.

Translational Research – Defining the “T’s” | Translational Cancer Research Network. (n.d.). Www.Tcrn.Unsw.Edu. Retrieved June 18, 2021, from

A Sample Answer 2 For the Assignment: NURS 550 Discussion Levels of Translational Research

Title:  NURS 550 Discussion Levels of Translational Research

Translational research is a new concept in my view of the world, it is a fairly new concept, as nurses we hear the term evidence-based practice (EBP) and research. Translational research is often thought of as EPB, Translational research is the research of EBP studies as well as the study and translation of EBP interventions into practice (Melnyk & Fineout-Overholt, 2019) Translational research is as stated it translates how EBP “translates” into practice, evidence-based practice is a guide to practice, translation science is the translation to implement the evidence-based research into practice. (Tilter, 2018). Translation research has different components to implementation of preclinical studies, phase one small clinical trials, phase 2&3 larger clinical trials, outcomes from the clinical trials, them phase 5 population outcomes research- these phases offer a “bench to bedside” continuum (Tilter, 2018).

Gaps between the availability of evidence and the placing evidence into practice has shown to partner with poor outcomes by not enabling caregivers to place the evidence into practice. (Tilter, 2018)Transitional research has shown to be beneficial in-patient outcomes and health care management by translating the evidence into practice which improves patient outcomes by the utilization of the evidence. In my field of Labor and delivery I have seen this similar process in the abundance availability of research and evidence of the increased risk of hypertension in pregnancy. Yet the physicians I practice with implement in very many ways through lack of translation causing early inductions and higher risk to the infants. When implementing a new technology, evidence or practice it is important to understand the research and evidence behind it as well as how best to safely implement into practice. (Sung et al., 2020) Translation research is an exciting and has multiple opportunities to advance patient outcomes, as an upcoming APRN in a magnet hospital, utilizing this process with EBP will strongly improve patient care as well as nursing practice.



Melnyk, B. M., PhD, RN. APRN-CNP, FAANP, FNAP, FAAN, & Fineout-Overholt, E., PhD, RN, FNAP, FAAN. (2019). Evidence-Based Practice in Nursing& Healthcare A Guide to Best Practice (4th ed.). Wolters Kluwer.

Sung, V. W., MD MPH, Tulikangas, P., MD, Bradley, C. S., MD, MSCE, & Rideway, B., MD. (2020). Assessing and adopting New medical devices for Obstetric and Gynecologic care. ACOG135(4), 160–166. Retrieved May 26, 2021, from

Tilter, M. G. (2018). Translation Research in Practice: An Introduction. Online Journal of Issues in Nursing23(2). Retrieved June 16, 2021,

A Sample Answer 3 For the Assignment: NURS 550 Discussion Levels of Translational Research

Title:  NURS 550 Discussion Levels of Translational Research

As nurses, we all have heard about evidence-based practice and Florence Nightingale. Although back then, the term evidence-based practice was not a common phrase, that is exactly what Florence Nightingale was doing back then. She would examine and experiment with the sanitary conditions of the facilities and look at how it affected the patient’s outcomes (Mackey & Bassendowski, 2017). Translational research is more of a newer terminology. Although it can be confused with evidence-based practice, there is a key distinction. Evidence-based practice is the act of applying the evidence into everyday practice, whereas translational research is more the act of conducting the studies to find the best evidence (Titler, 2018).

There are strict guidelines when conducting translational research or what many of us know as clinical trials. There is phase process where in order to progress to the next phase of clinical trials, they must meet certain criteria. New drugs must undergo in vitro preclinical trials where they are testing it in a laboratory setting instead of human trials. Then they can proceed to in vivo studies where they are studying it in animals and small sample size of human trials (Eske, 2020). Once it has proven to be safe, then they can progress to a phase two or three trial increasing the sample size and comparing it to common treatments or sometimes placebos. Once it has shown safety and efficacy in a phase two or three trial, it can then go for Food and Drug Administration (FDA) approval. There are also phase four and five trials that help with translating the evidence into practice and community settings (Titler, 2018).

In my specialty area of oncology, we are constantly hearing about clinical trials and new therapies coming to market. It is critical to have a good understanding of what each phase of the trial consists of and what the outcomes really mean to the patient.


Eske, J. (2020, August 31). In vivo vs. in vitro: What is the difference? Medical News Today. Retrieved June 17, 2021, from

Mackey, A., & Bassendowski, S. (2017). The history of evidence-based practice in nursing education and practice. Journal of Professional Nursing33(1), 51–55.

Titler, M. G. (2018). Translation Research in Practice: An Introduction. Online Journal of Issues in Nursing23(2).

Topic 1 Participation


Topic 1: Quality Research and Theoretical Frameworks



1. Identify the different levels of translational research.
2. Differentiate translational research from evidence-based practice.
3. Discuss the application of translational research to population health management.
4. Evaluate sources of translational research.
5. Select a valid nursing practice problem for an evidence-based practice project proposal.
Study Materials
Advanced Practice Nursing: Essential Knowledge for the Profession
Read Chapters 22 and 23 in Advanced Practice Nursing: Essential Knowledge for the Profession.
Evidence-Based Practice in Nursing and Healthcare
Read Chapter 1 in Evidence-Based Practice in Nursing and Healthcare.
World Health Organization (WHO)
Explore the World Health Organization (WHO) website. Centers for Disease Control and Prevention (CDC)

Explore the Centers for Disease Control and Prevention (CDC) website.

NURS 550 Discussion Levels of Translational Research
NURS 550 Discussion Levels of Translational Research

State and County Departments of Health
Explore the websites of your state and county departments of health and access mortality and morbidity data. The link to the Arizona Department of Health Services website is provided, but students living in other states should access their county and state departments.
Non-Communicable Diseases (NCD) Burden of Disease
Read “Non-Communicable Diseases (NCD) Burden of Disease,” by the U.S. Department of Health and Human Services, located on the Centers for Disease Control and Prevention website.

Click here to ORDER an A++ paper from our MASTERS and DOCTORATE WRITERS: NURS 550 Discussion Levels of Translational Research

GCU Library: Nursing and Health Sciences Research Guide
Review the “Nursing and Health Sciences” research guide, located on the GCU Library website.
The Electronic Health Record: A Friend or Foe of Translational Research and Evidence-Based Practice?
Read “The Electronic Health Record: A Friend or Foe of Translational Research and Evidence-Based Practice?” by Chipps et al., from Worldviews on Evidence-Based Nursing (2019).
Evidence-Based Practice
Read “Evidence-Based Practice” by Melnyk and Fineout-Overholt, from Encyclopedia of Nursing Research (2017).
Translation Research in Practice: An Introduction
Read “Translation Research in Practice: An Introduction,” by Titler, from Online Journal of Issues in Nursing (2018).
On Biostatistics and Clinical Trials: PICO, PICOTS, PICOTT Framework for Clinical Questions as a Way to Design Clinical Trials
Read “PICO, PICOTS, PICOTT Framework for Clinical Questions as a Way to Design Clinical Trials,” by Deng, from
On Biostatistics and Clinical Trials (2020).
Course Description
In this course learners examine the process of scientific inquiry, knowledge generation, utilization, and dissemination of evidence into advanced nursing practice in order to propose quality-improvement initiatives that advance the delivery of safe, high-quality care for patient populations. Learners critically evaluate evidence, including scientific findings from the biopsychosocial fields, epidemiology, biostatistics, genetics, and genomics, and apply levels of evidence and theoretical frameworks to design culturally appropriate clinical prevention interventions and population-based care that reduces risks, prevents disease, and promotes health and well-being. Learners also consider strategies to evaluate health policy and advocacy issues, the state of health care delivery, patient-centered care, and ethical principles related to health beliefs, health promotion, and risk reduction for diverse populations. Learners apply these strategies to work towards recognizing gaps in nursing and health care knowledge, identifying potential solutions or innovations for those gaps, planning and implementing practice changes, and evaluating the outcomes in order to improve practice. Prerequisite: NUR-513.
Course Materials

Nash, D. B., Fabius, R. J., Skoufalos, A., Clarke, J. L., & Horowitz, M. R. (2019). Population health: Creating a culture of wellness (3rd ed.). Jones & Bartlett Learning. ISBN-13: 9781284047929
Evidence-Based Practice in Nursing and Healthcare : A Guide to Best Practice
Melnyk, B. M., & Fineout-Overholt, E. (2019). Evidence-based practice in nursing and healthcare: A guide to best practice (4th ed.). Wolters Kluwer. ISBN-13: 9781496384539
APA Writing Style
APA Style is required for all writing assignments in this course, where indicated. Please prepare these assignments according to the APA Style Guide, located in the in the Student Success Center.
You may want to consider purchasing a copy of the APA style guide, as this will be a useful resource throughout your program
The Writing Process Access
View “The Writing Process” media presentation for information on how to strengthen your writing for future assignments.
University Policy Handbook
Read the Code of Conduct and Academic Standards section of the University Policy Handbook.
Library Walk Through Tutorial
View the “Library Walk Through Tutorial.”
Academic Integrity
Read the “About LopesWrite” and “Plagiarism” sections of the Academic Integrity page of the GCU website.
GCU Library: General Research Guide
Review the “General Research” guide, located on the GCU Library website.
GCU Library: Persistent Links
Review “Persistent Links,” located on the GCU Library website, to learn how to locate persistent links for library articles, videos, etc.
RefWorks and EndNote: RefWorks and EndNote Login
Manage your citations with the RefWorks tool, located on the GCU Library website. RefWorks automates the creation of your reference lists in the format of your choice (APA, MLA, etc.).
GCU Library Research Guides: Citing Sources
Reference the “GCU Library Research Guides: Citing Sources” resource for information on how to cite sources properly.
Writing Center
Refer to the resources located in the Writing Center for PowerPoint guidelines, APA style, writing and library tutorials, and research and writing assistance.
Statement on the Integration of Faith and Work
“Grand Canyon University prepares learners to become global citizens, critical thinkers, effective communicators, and responsible leaders by providing an academically-challenging, values-based curriculum from the context of our Christian heritage” (GCU Mission Statement). Review the “Statement on the Integration of Faith and Work” to become familiar with many fundamental Christian worldviews and consider how they may apply in the context of this course.

Lopes Write Policy

For assignments that need to be submitted to Lopes Write, please be sure you have received your report and Similarity Index (SI) percentage BEFORE you do a “final submit” to me.

Once you have received your report, please review it. This report will show you grammatical, punctuation, and spelling errors that can easily be fixed. Take the extra few minutes to review instead of getting counted off for these mistakes.

Review your similarities. Did you forget to cite something? Did you not paraphrase well enough? Is your paper made up of someone else’s thoughts more than your own?

Visit the Writing Center in the Student Success Center, under the Resources tab in LoudCloud for tips on improving your paper and SI score.

Late Policy

The university’s policy on late assignments is 10% penalty PER DAY LATE. This also applies to late DQ replies.

Please communicate with me if you anticipate having to submit an assignment late. I am happy to be flexible, with advance notice. We may be able to work out an extension based on extenuating circumstances.

If you do not communicate with me before submitting an assignment late, the GCU late policy will be in effect.

I do not accept assignments that are two or more weeks late unless we have worked out an extension.

As per policy, no assignments are accepted after the last day of class. Any assignment submitted after midnight on the last day of class will not be accepted for grading.


Communication is so very important. There are multiple ways to communicate with me:

Questions to Instructor Forum: This is a great place to ask course content or assignment questions. If you have a question, there is a good chance one of your peers does as well. This is a public forum for the class.

Individual Forum: This is a private forum to ask me questions or send me messages. This will be checked at least once every 24 hours.

Important information for writing discussion questions and participation

Welcome to class

Hello class and welcome to the class and I will be your instructor for this course. This is a -week course and requires a lot of time commitment, organization, and a high level of dedication. Please use the class syllabus to guide you through all the assignments required for the course. I have also attached the classroom policies to this announcement to know your expectations for this course. Please review this document carefully and ask me any questions if you do. You could email me at any time or send me a message via the “message” icon in halo if you need to contact me. I check my email regularly, so you should get a response within 24 hours. If you have not heard from me within 24 hours and need to contact me urgently, please send a follow up text to

I strongly encourage that you do not wait until the very last minute to complete your assignments. Your assignments in weeks 4 and 5 require early planning as you would need to present a teaching plan and interview a community health provider. I advise you look at the requirements for these assignments at the beginning of the course and plan accordingly. I have posted the YouTube link that explains all the class assignments in detail. It is required that you watch this 32-minute video as the assignments from week 3 through 5 require that you follow the instructions to the letter to succeed. Failure to complete these assignments according to instructions might lead to a zero. After watching the video, please schedule a one-on-one with me to discuss your topic for your project by the second week of class. Use this link to schedule a 15-minute session. Please, call me at the time of your appointment on my number. Please note that I will NOT call you.

Please, be advised I do NOT accept any assignments by email. If you are having technical issues with uploading an assignment, contact the technical department and inform me of the issue. If you have any issues that would prevent you from getting your assignments to me by the deadline, please inform me to request a possible extension. Note that working fulltime or overtime is no excuse for late assignments. There is a 5%-point deduction for every day your assignment is late. This only applies to approved extensions. Late assignments will not be accepted.

If you think you would be needing accommodations due to any reasons, please contact the appropriate department to request accommodations.

Plagiarism is highly prohibited. Please ensure you are citing your sources correctly using APA 7th edition. All assignments including discussion posts should be formatted in APA with the appropriate spacing, font, margin, and indents. Any papers not well formatted would be returned back to you, hence, I advise you review APA formatting style. I have attached a sample paper in APA format and will also post sample discussion responses in subsequent announcements.

Your initial discussion post should be a minimum of 200 words and response posts should be a minimum of 150 words. Be advised that I grade based on quality and not necessarily the number of words you post. A minimum of TWO references should be used for your initial post. For your response post, you do not need references as personal experiences would count as response posts. If you however cite anything from the literature for your response post, it is required that you cite your reference. You should include a minimum of THREE references for papers in this course. Please note that references should be no more than 5 years old except recommended as a resource for the class. Furthermore, for each discussion board question, you need ONE initial substantive response and TWO substantive responses to either your classmates or your instructor for a total of THREE responses. There are TWO discussion questions each week, hence, you need a total minimum of SIX discussion posts for each week. I usually post a discussion question each week. You could also respond to these as it would count towards your required SIX discussion posts for the week.

I understand this is a lot of information to cover in 5 weeks, however, the Bible says in Philippians 4:13 that we can do all things through Christ that strengthens us. Even in times like this, we are encouraged by God’s word that we have that ability in us to succeed with His strength. I pray that each and every one of you receives strength for this course and life generally as we navigate through this pandemic that is shaking our world today. Relax and enjoy the course!

Hi Class,

Please read through the following information on writing a Discussion question response and participation posts.

Contact me if you have any questions.

Important information on Writing a Discussion Question

  • Your response needs to be a minimum of 150 words (not including your list of references)
  • There needs to be at least TWO references with ONE being a peer reviewed professional journal article.
  • Include in-text citations in your response
  • Do not include quotes—instead summarize and paraphrase the information
  • Follow APA-7th edition
  • Points will be deducted if the above is not followed

Participation –replies to your classmates or instructor

  • A minimum of 6 responses per week, on at least 3 days of the week.
  • Each response needs at least ONE reference with citations—best if it is a peer reviewed journal article
  • Each response needs to be at least 75 words in length (does not include your list of references)
  • Responses need to be substantive by bringing information to the discussion or further enhance the discussion. Responses of “I agree” or “great post” does not count for the word count.
  • Follow APA 7th edition
  • Points will be deducted if the above is not followed
  • Remember to use and follow APA-7th edition for all weekly assignments, discussion questions, and participation points.
  • Here are some helpful links
  • Student paper example
  • Citing Sources
  • The Writing Center is a great resource