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NUR 550 Topic 1 Discussion Question one

NUR 550 Topic 1 Discussion Question one

Identify the different levels of translational research. Explain how translational research is different from evidence-based practice and discuss application to population health management.

Re: Topic 1 DQ 1

Translational research is form of clinical research that was first seen around 1993 (Rubio et al, 2010). So as far as research goes this is a fairly new was to look into things. There is also no clear definition of translational research, but essentially it encompasses two areas of translation one being the information obtained in pre-clinical studies, lab research and the other being the adaptation of best practices in the community with their cost effectiveness (Rubio et al, 2010). There are three levels of translational research, starting with T1, which involves the beginning research or development of an intervention, including the lab research, observational research and phase I and II clinical trials (Translational Research, n.d.). The second level is T2 the translation to patients, testing these interventions and their efficacy on the patient populace, including phase III clinical trials, studying how these new interventions work with disease processes and creating new guidelines with up-to-date information (Translational Research, n.d.). The third level is T3 disseminating and implementation of all the research into daily practice, creating the research evidence found into evidence-based practices across the profession (Translational Research, n.d.).

From this information there isn’t a difference between evidence-based practice and translational research, it is just a way to get to evidence based practice. By following the ‘three T’s’, the final step is to put all of this research into practice, as evidence-based practice. For public health this means the most up to date care and information as the natural progression of translational practice ends with practice. If there is no research being done in the area however, this has a negative impact on the population, as there is not up to date EPB related to that disease process and/or its co morbidities.

Rubio, D. M., Schoenbaum, E. E., Lee, L. S., Schteingart, D. E., Marantz, P. R., Anderson, K. E., Platt, L. D., Baez, A., & Esposito, K. (2010). Defining translational research: implications for training. Academic medicine : journal of the Association of American Medical Colleges85(3), 470–475. https://doi.org/10.1097/ACM.0b013e3181ccd618

Translational Research – Defining the “T’s” | Translational Cancer Research Network. (n.d.). Www.Tcrn.Unsw.Edu. Retrieved June 18, 2021, from http://www.tcrn.unsw.edu.au/translational-research-definitions

 

RESPOND HERE (150 W0ORDS, 2 REFERENCES)

 

This is insightful Sarah, translational research is form of clinical research that was first seen around 1993. So as far as research goes

NUR 550 Topic 1 Discussion Question one

NUR 550 Topic 1 Discussion Question one

this is a fairly new was to look into things. Translational research refers to a form of study that seeks to produce more applicable, meaningful and valid outcomes that can directly impact human health. The main objective or purpose of the translational research is to translate essential science discoveries more quickly and efficiently into practices (Eske, 2020). Translational research has been applied frequently by different researchers to enhance research processes geared towards achieving quality treatment processes and effective patient outcomes. There are three major level of translational research including T1, T2, and T3. These levels need to be incorporated into the research processes to ensure accuracy and effective outcomes in the research processes (Woolf, 2018). Level I or T1 often involves development of interventions to ensure that the entire research processes is done effectively in line with the set objectives.

References

Woolf, S. H. (2018). The meaning of translational research and why it matters. Jama299(2), 211-213. https://jamanetwork.com/journals/jama/article-abstract/1149350

Eske, J. (2020, August 31). In vivo vs. in vitro: What is the difference? Medical News Today. Retrieved June 17, 2021, from https://www.medicalnewstoday.com/articles/in-vivo-vs-in-vitro

Re: Topic 1 DQ 1

Translational research is a new concept in my view of the world, it is a fairly new concept, as nurses we hear the term evidence-based practice (EBP) and research. Translational research is often thought of as EPB, Translational research is the research of EBP studies as well as the study and translation of EBP interventions into practice (Melnyk & Fineout-Overholt, 2019) Translational research is as stated it translates how EBP “translates” into practice, evidence-based practice is a guide to practice, translation science is the translation to implement the evidence-based research into practice. (Tilter, 2018). Translation research has different components to implementation of preclinical studies, phase one small clinical trials, phase 2&3 larger clinical trials, outcomes from the clinical trials, them phase 5 population outcomes research- these phases offer a “bench to bedside” continuum (Tilter, 2018).

Gaps between the availability of evidence and the placing evidence into practice has shown to partner with poor outcomes by not enabling caregivers to place the evidence into practice. (Tilter, 2018)Transitional research has shown to be beneficial in-patient outcomes and health care management by translating the evidence into practice which improves patient outcomes by the utilization of the evidence. In my field of Labor and delivery I have seen this similar process in the abundance availability of research and evidence of the increased risk of hypertension in pregnancy. Yet the physicians I practice with implement in very many ways through lack of translation causing early inductions and higher risk to the infants. When implementing a new technology, evidence or practice it is important to understand the research and evidence behind it as well as how best to safely implement into practice. (Sung et al., 2020) Translation research is an exciting and has multiple opportunities to advance patient outcomes, as an upcoming APRN in a magnet hospital, utilizing this process with EBP will strongly improve patient care as well as nursing practice.

 

References

Melnyk, B. M., PhD, RN. APRN-CNP, FAANP, FNAP, FAAN, & Fineout-Overholt, E., PhD, RN, FNAP, FAAN. (2019). Evidence-Based Practice in Nursing& Healthcare A Guide to Best Practice (4th ed.). Wolters Kluwer.

Sung, V. W., MD MPH, Tulikangas, P., MD, Bradley, C. S., MD, MSCE, & Rideway, B., MD. (2020). Assessing and adopting New medical devices for Obstetric and Gynecologic care. ACOG135(4), 160–166. Retrieved May 26, 2021, from

Tilter, M. G. (2018). Translation Research in Practice: An Introduction. Online Journal of Issues in Nursing23(2). Retrieved June 16, 2021, from

Description:

Identify the different levels of translational research. Explain how translational research is different from evidence-based practice and discuss its application to population health management.

Description

Objectives:

1. Identify the different levels of translational research.
2. Differentiate translational research from evidence-based practice.
3. Discuss the application of translational research to population health management.
4. Evaluate sources of translational research.
5. Select a valid nursing practice problem for an evidence-based practice project proposal.

Advanced Practice Nursing: Essential Knowledge for the Profession

Description:

Read Chapters 22 and 23 in Advanced Practice Nursing: Essential Knowledge for the Profession.

Evidence-Based Practice in Nursing and Healthcare

Description:

Read Chapter 1 in Evidence-Based Practice in Nursing and Healthcare.

World Health Organization (WHO)

Description:

Explore the World Health Organization (WHO) website.

Centers for Disease Control and Prevention (CDC)

Description:

Explore the Centers for Disease Control and Prevention (CDC) website.

State and County Departments of Health

 

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Description:

Explore the websites of your state and county departments of health and access mortality and morbidity data. The link to the Arizona Department of Health Services website is provided, but students living in other states should access their county and state departments.

Non-Communicable Diseases (NCD) Burden of Disease

Description:

Read “Non-Communicable Diseases (NCD) Burden of Disease,” by the U.S. Department of Health and Human Services, located on the Centers for Disease Control and Prevention website.

GCU Library: Nursing and Health Sciences Research Guide

Description:

Review the “Nursing and Health Sciences” research guide, located on the GCU Library website.

The Electronic Health Record: A Friend or Foe of Translational Research and Evidence-Based Practice?
Description:

Read “The Electronic Health Record: A Friend or Foe of Translational Research and Evidence-Based Practice?” by Chipps et al., from Worldviews on Evidence-Based Nursing (2019).

Evidence-Based Practice

Description:

Read “Evidence-Based Practice” by Melnyk and Fineout-Overholt, from Encyclopedia of Nursing Research (2017).

Translation Research in Practice: An Introduction

Description:

Read “Translation Research in Practice: An Introduction,” by Titler, from Online Journal of Issues in Nursing (2018).

On Biostatistics and Clinical Trials: PICO, PICOTS, PICOTT Framework for Clinical Questions as a Way to Design Clinical Trials
Description:

Read “PICO, PICOTS, PICOTT Framework for Clinical Questions as a Way to Design Clinical Trials,” by Deng, from
On Biostatistics and Clinical Trials (2020).

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