NR 507 Week 8 Discussion : Genomes, Genetic Alterations, and Reproductive Disorders

Sample Answer for NR 507 Week 8 Discussion : Genomes, Genetic Alterations, and Reproductive Disorders Included After Question

NR 507 Week 8: Genomes, Genetic Alterations, and Reproductive Disorders

NR 507 Week 8 Discussion Genomes, Genetic Alterations, and Reproductive Disorders

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Week 8: Open Forum Discussion

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A Sample Answer For the Assignment: NR 507 Week 8 Discussion : Genomes, Genetic Alterations, and Reproductive Disorders

Title: NR 507 Week 8 Discussion : Genomes, Genetic Alterations, and Reproductive Disorders

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Aug 29, 2018Aug 29 at 11:06am

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Hello Professor and Class,

This week, one of the concepts we read about is genotype (genetic characteristics) and phenotype (physical characteristics) in males and females. I am particularly interested in how genotype and phenotype influence disease states in twins and whether twins have the same health problems. The reading indicates if one twin is diagnosed with a disease, the other twin has a higher risk of developing the same disease. My question is, “Does the risk of getting a particular disease increase or decrease more among identical twins or fraternal twins?”

Ingrid Spence

Aug 29, 2018Aug 29 at 2:38pm

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I did some research, and I found out the answer to your question. Twins share the same genes, but their environments become more different as they age. This unique aspect of twins makes them an exceptional model to considerate how genes and the environment donate to certain traits, extraordinarily complex behaviors, and diseases.
According to the article, an example of how genetic disease is when just one twin gets a disease, researchers can look for elements in the twins’ environments that are different. Or when both twins get a disease, researchers can look for genetic factors shared among similar twin pairs. These types of data are extraordinarily powerful when collected from large numbers of twins. Such studies can help pinpoint the molecular mechanism of a disease and determine the extent of environmental influence, potentially leading to the prevention and treatment of complex diseases.
To illustrate, for twins with schizophrenia, 50% of identical twins share the disease, while only about 10-15% of fraternal twins do. This difference is evidence for a strong genetic component in susceptibility to schizophrenia. However, the fact that both identical twins in a pair don’t develop the disease 100% of the time indicates that other factors are involved. I hope that helped to give you a better understanding of the disease process among twins.
Comparing Identical and Fraternal Twins: A higher percentage of disease incidence in both identical twins are the first indication of a genetic component. Rates lower than 100% in identical twins indicates that DNA alone does not determine susceptibility to disease.

Ingrid

Reference NR 507 Week 8 Discussion : Genomes, Genetic Alterations, and Reproductive Disorders

Insights from Identical Twins 2018, Retrieved from, https://learn.genetics.utah.edu/content/epigenetics/twins

Aug 29, 2018Aug 29 at 6:37pm

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Dr. Arredondo and class,

It is so hard to believe that we are finally in the last week of this class. I have learned so much during this class and gained knowledge about the body systems and disease processed that I can use in the workplace at this time as well as the nurse practitioner. This week we learned about genes and the reproductive system. I have always found genomics so interesting because it is this study that reveals why we as individual human beings are the way we are. From physical characteristics to hereditary disorders genomics attempts to gain an understanding of how these traits are passed down from parent to offspring. Another topic that I have a special interest in is the reproductive disorders of the female. One disorder that is always so interesting to me is uterine fibroids. This disorder causes symptoms in women such as severe bleeding during menstrual cycles, abdominal pain, and distention. I see this occurrence many times in the workplace and had the opportunity in a past specialty placement to nurse women who had this disorder and would often have to undergo a myomectomy to remove the fibroids or in some cases even a hysterectomy to prevent the reoccurrence of fibroids. The male and female reproductive systems are very interesting and also help us to gain an understanding of the process of conception and for women the pregnancy process. I am so thankful for all of the knowledge gained from this course and very nervous about this final exam. I wish everyone the best of luck and hope we all continue this journey together.

Aug 30, 2018Aug 30 at 9:55am

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NR 507 WK 8 Open Forum Final Post

Stacy Cooper

Professor and Class,

This week’s lesson explored the concepts related to genomics, genetics and both male and female reproductive systems. In which the female reproductive complications, and various interventions aimed at female reproduction were more intriguing, to the student. Although I had a basic understanding of the pathological process affecting women that have chronic complications with menstruation. A significant number of women often have an end result of either having a version of a hysterectomy or surgical ablation related to excessive blood loss. The readings provided a more in depth understanding of issues faced by women across multiple ethnicities. In which the student garnered a continued understanding about uterine fibroids, being classified as benign tumors with the propensity to develop into a metastatic neoplasm. In addition to learning that sexually transmitted diseases such as chlamydia and gonorrhea were not necessarily the cause for pelvic inflammatory disease, but an associated risk factor. Contributing to infertility and other various reproductive complications “(McCance, Huether, Brashers, & Rote, 2014). The lesson on female reproductive health, allowed the student to be able to process, how and why television commercials and obstetricians promote hormone replacement therapy, and/or intrauterine contraceptive devices. As research has shown these interventions can improve complications associated with dysmenorrhea, and potentially reduce the need for invasive surgical intervention (McCance et al., 2014). I have enjoyed participating in this online class and forum with each of you. Especially the exchange and knowledge in which we all contributed to. I would like to wish everyone prosperity and success and we progress towards meeting our goal of becoming family nurse practitioners.

Respectfully submitted,

Stacy Cooper

References NR 507 Week 8 Discussion : Genomes, Genetic Alterations, and Reproductive Disorders

McCance, K. L., Huether, S. E., Brashers, V. L., & Rote, N. S. (2014). Pathophysiology: The biologic basis for disease in adults and children (7th ed.). St. Louis, Missouri: Mosby

Aug 30, 2018Aug 30 at 2:05pm

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Dr. Arredondo and Class,

This week’s lesson covered important information regarding genetics and the male/female reproductive system. DNA is the basis of life and provides all cells with the instructions needed to perform designated functions. DNA’s instructions are carried out by RNA. This week’s lesson also covered information about dominant and recessive genes. It is important to understand what diseases and defects are recessive and which are dominant. This information is important for patients to understand when planning on conceiving a child. Potential parents should be educated on the risks of conceiving a child with the concerning defect. The information on the male and female reproductive system covered this week involved dysfunction of the system. These dysfunctions can be a normal part of aging, but should be brought to a primary providers attention to ensure the condition is benign.

Aug 31, 2018Aug 31 at 12:40pm

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Hello, Dr. Arredondo and Class

I would like to say that am finally done with this class. I just completed my final exam. It looks simple but not that simple. I am glad I passed the class, that’s what matters. Good luck to everyone.

This week’s lesson covered the basics of genetics, environment and common illnesses. Virtually all human being diseases arise from the synergy of genetic predisposition determinants and adaptable environmental determinants vastly delineated to incorporate infectious, chemical, physical, dietary and behavioral determinants (McCance, Huether, Brashers, & Rote, 2013).We also covered the topic on the structure and function of male and female reproductive structures which rely on hormonal steroids called sex hormones and their prototypes. These hormonal effects start the effects of reproductive structures which begin prior to birth and persist for life (McCance, Huether, Brashers, & Rote, 2013). Variations of the reproductive structure cover a broad range of issues, from deferred sexual growth and substandard sexual accomplishment to anatomical and functional anomalies (McCance, Huether, Brashers, & Rote, 2013). Sexual or reproductive malfunction, like erectile dysfunction or infertility, can suddenly affect self-image, relationships and general quality of life (McCance, Huether, Brashers, & Rote, 2013).

Mwiche-

References NR 507 Week 8 Discussion : Genomes, Genetic Alterations, and Reproductive Disorders

McCance, K. L., Huether, S. E., Brashers, V. L., & Rote, N. S. (2013). Pathophysiology: The biologic basis for disease in adults and children (7th ed.). St. Louis, MO: Mosby

Aug 31, 2018Aug 31 at 12:58pm

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Dr. Arredondo and class,

This week I have learned about the pelvic inflammatory disease. Pelvic inflammatory disease (PID) is an infection of the female reproductive organs. It is a common illness. PID is diagnosed in more than 1 million women each year in the United States. PID occurs when bacteria move from the vagina and cervix upward into the uterus, ovaries, or fallopian tubes. The bacteria can lead to an abscess in a fallopian tube or ovary. Long-term problems can occur if PID is not treated promptly. Two sexually transmitted infections are gonorrhea and chlamydia. Gonorrhea and chlamydia may cause vague symptoms or even no symptoms in a woman. When a woman is infected with gonorrhea or chlamydia and does not receive treatment, it can take anywhere from a few days to a few weeks before she develops PID. PID also can be caused by infections that are not sexually transmitted, such as bacterial vaginosis. Patients should be educated on the importance of practicing safe sex to prevent them from being infected with sexually transmitted infections that increase the risks of PID. Wishing everyone the best in their future courses.

Aug 31, 2018Aug 31 at 6:20pm

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Dr. Arrendondo and class,

This week’s lesson on genetics and diseases of the reproductive systems assisted me in further advancing my knowledge on these subjects. I found it very interesting the difference between genotype and phenotype. I suppose I had forgotten what the specifics of these were and found the discussion of twins to be interesting. In the lesson, it discussed how twin’s phenotype’s can be different based on their environment and life choices, such as smoking. Although they may have the same genotype, they can have a vast difference in their phenotype. I have learned quite a bit in the last eight weeks about pathophysiology and hope to apply this knowledge in my future practice.

Sep 1, 2018Sep 1 at 3:18am

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This class has provided me with a conceptual overview of pathophysiology and mechanisms of disease; I believe that this course was designed to ease the transition from the basic sciences to the clinical years. I think that this course can be very helpful to m self as a FNP and other health care professionals because it shows the clinical relevance of the basic sciences through overall principles and understanding.

Sep 1, 2018Sep 1 at 11:19am

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Dr. Arredondo and Class,

It has been a pleasure communicating and sharing information regarding pathophysiology with all of you.

I have learned many new things and refreshed my memory in some areas during my time in this class. I enjoyed reading about genetics and learning how genes and environment both play a role in disease chance. I also enjoyed reading the chapters on hormones and hormone regulation in the body. I found pictures or diagrams of hormone origination and target organs especially helpful in

remembering this complex system. I also learned that keeping up with weekly readings and homework assignments is the best way to be successful in class. Cramming does not work in these intense classes, so staying on top of school work is a priority.

See you all in advanced pharmacology

Regards,

Julie

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