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Assignment NURS  6630 Therapy for Patients With Major Depressive Disorder (MDD)

Assignment: NURS  6630 Therapy for Patients With Major Depressive Disorder (MDD)

Mood disorders can impact every facet of a human being’s life, making the most basic activities difficult
for patients and their families. This was the case for 13-year-old Jeanette, who was struggling at home
and at school. For more than 8 years, Jeanette suffered from temper tantrums, impulsiveness,
inappropriate behavior, difficulty in judgment, and sleep issues.
As a PNP working with pediatric patients, you must be able to assess whether these symptoms are
caused by psychological, social, or underlying growth and development issues. You must then be able
recommend appropriate therapies.
This week, as you examine antidepressant therapies, you explore the assessment and treatment of
three populations: pediatrics, adults, and geriatrics. The focus of your assessment tool, a decision tree,
will specifically center on one of the most vulnerable populations, pediatrics. Please remember, you
must also consider the ethical and legal implications of these therapies. You will also complete a Quiz on
the concepts addressed throughout this module.
Learning Objectives
Students will:
 Assess patient factors and history to develop personalized plans of antidepressant therapy
across the lifespan
 Analyze factors that influence pharmacokinetic and pharmacodynamic processes in pediatric,
adult, and geriatric patients requiring antidepressant therapy
 Synthesize knowledge of providing care to pediatric, adult, and geriatric patients presenting for
antidepressant therapy
 Analyze ethical and legal implications related to prescribing antidepressant therapy to patients
across the lifespan

Learning Resources

Required Readings (click to expand/reduce)

Baek, J. H., Nierenberg, A. A., & Fava, M. (2016). Pharmacological approaches to treatment-resistant
depression. In T. A. Stern, M. Favo, T. E. Wilens, & J. F. Rosenbaum. (Eds.), Massachusetts General
Hospital psychopharmacology and neurotherapeutics (pp. 44–47). Elsevier.
Fava, M., & Papakostas, G. I. (2016). Antidepressants. In T. A. Stern, M. Favo, T. E. Wilens, & J. F.
Rosenbaum. (Eds.), Massachusetts General Hospital psychopharmacology and neurotherapeutics (pp.
27–43). Elsevier.

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th
ed.). https://doi.org/10.1176/appi.books.9780890425596

Howland, R. H. (2008a). Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Part 1:
Study design. Journal of Psychosocial Nursing and Mental Health Services, 46(9), 21–24.

Howland, R. H. (2008b). Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Part 2:
Study outcomes. Journal of Psychosocial Nursing and Mental Health Services, 46(10), 21–24.

Assignment NURS  6630 Therapy for Patients With Major Depressive Disorder (MDD)

Assignment NURS  6630 Therapy for Patients With Major Depressive Disorder (MDD)

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Lorberg, B., Davico, C., Martsenkovskyi, D., & Vitiello, B. (2019).  Principles in using psychotropic
medication in children and adolescents. In J. M. Rey & A. Martin (Eds.), IACAPAP e-textbook of child and
adolescent mental
health. https://iacapap.org/_Resources/Persistent/a97650fb538f47bb697c47873b0e58d493684a07/A.7

Magellan Health. (2013). Appropriate use of psychotropic drugs in children and adolescents: A clinical
monograph. http://www.magellanhealth.com/media/445492/magellan-psychotropicdrugs-0203141.pdf

Poznanski, E. O., & Mokros, H. B. (1996). Child depression rating scale—Revised. Western Psychological

Rao, U. (2013). Biomarkers in pediatric depression. Depression & Anxiety, 30(9), 787–791.

Yasuda, S. U., Zhang, L. & Huang, S.-M. (2008). The role of ethnicity in variability in response to drugs:
Focus on clinical pharmacology studies. Clinical Pharmacology & Therapeutics, 84(3), 417–423.

Medication Resources (click to expand/reduce)

U.S. Food & Drug Administration. (n.d.). Drugs@FDA: FDA-approved drugs.

Note: To access the following medications, use the Drugs@FDA resource. Type the name of each
medication in the keyword search bar. Select the hyperlink related to the medication name you
searched. Review the supplements provided and select the package label resource file associated with
the medication you searched. If a label is not available, you may need to conduct a general search
outside of this resource provided. Be sure to review the label information for each medication as this
information will be helpful for your review in preparation for your Assignments.
Review the following medications:
 amitriptyline
 bupropion
 citalopram
 clomipramine
 desipramine
 desvenlafaxine
 doxepin
 duloxetine
 escitalopram
 fluoxetine
 fluvoxamine

 imipramine
 ketamine
 mirtazapine
 nortriptyline
 paroxetine
 selegiline
 sertraline
 trazodone
 venlafaxine
 vilazodone
 vortioxetine

Required Media (click to expand/reduce)

Case Study: An African American Child Suffering from Depression
Note: This case study will serve as the foundation for this week’s Assignment.

Optional Resources (click to expand/reduce)

El Marroun, H., White, T., Verhulst, F., & Tiemeier, H. (2014). Maternal use of antidepressant or
anxiolytic medication during pregnancy and childhood neurodevelopmental outcomes: A systematic
review. European Child & Adolescent Psychiatry, 23(10), 973–992. https://doi.org/10.1007/s00787-014-

Gordon, M. S., & Melvin, G. A. (2014). Do antidepressants make children and adolescents suicidal?
Journal of Pediatrics and Child Health, 50(11), 847–854. https://doi.org/10.1111/jpc.12655

Seedat, S. (2014). Controversies in the use of antidepressants in children and adolescents: A decade
since the storm and where do we stand now? Journal of Child & Adolescent Mental Health, 26(2),
iii–v. https://doi.org/10.2989/17280583.2014.938497

Important information for writing discussion questions and participation

Hi Class,

Please read through the following information on writing a Discussion question response and participation posts.

Contact me if you have any questions.

Important information on Writing a Discussion Question

  • Your response needs to be a minimum of 150 words (not including your list of references)
  • There needs to be at least TWO references with ONE being a peer reviewed professional journal article.
  • Include in-text citations in your response
  • Do not include quotes—instead summarize and paraphrase the information
  • Follow APA-7th edition
  • Points will be deducted if the above is not followed

Participation –replies to your classmates or instructor

  • A minimum of 6 responses per week, on at least 3 days of the week.
  • Each response needs at least ONE reference with citations—best if it is a peer reviewed journal article
  • Each response needs to be at least 75 words in length (does not include your list of references)
  • Responses need to be substantive by bringing information to the discussion or further enhance the discussion. Responses of “I agree” or “great post” does not count for the word count.
  • Follow APA 7th edition
  • Points will be deducted if the above is not followed

Welcome to class

Hello class and welcome to the class and I will be your instructor for this course. This is a -week course and requires a lot of time commitment, organization, and a high level of dedication. Please use the class syllabus to guide you through all the assignments required for the course. I have also attached the classroom policies to this announcement to know your expectations for this course. Please review this document carefully and ask me any questions if you do. You could email me at any time or send me a message via the “message” icon in halo if you need to contact me. I check my email regularly, so you should get a response within 24 hours. If you have not heard from me within 24 hours and need to contact me urgently, please send a follow up text to.

I strongly encourage that you do not wait until the very last minute to complete your assignments. Your assignments in weeks 4 and 5 require early planning as you would need to present a teaching plan and interview a community health provider. I advise you look at the requirements for these assignments at the beginning of the course and plan accordingly. I have posted the YouTube link that explains all the class assignments in detail. It is required that you watch this 32-minute video as the assignments from week 3 through 5 require that you follow the instructions to the letter to succeed. Failure to complete these assignments according to instructions might lead to a zero. After watching the video, please schedule a one-on-one with me to discuss your topic for your project by the second week of class. Use this link to schedule a 15-minute session. Please, call me at the time of your appointment on my number. Please note that I will NOT call you.

Please, be advised I do NOT accept any assignments by email. If you are having technical issues with uploading an assignment, contact the technical department and inform me of the issue. If you have any issues that would prevent you from getting your assignments to me by the deadline, please inform me to request a possible extension. Note that working fulltime or overtime is no excuse for late assignments. There is a 5%-point deduction for every day your assignment is late. This only applies to approved extensions. Late assignments will not be accepted.

If you think you would be needing accommodations due to any reasons, please contact the appropriate department to request accommodations.

Plagiarism is highly prohibited. Please ensure you are citing your sources correctly using APA 7th edition. All assignments including discussion posts should be formatted in APA with the appropriate spacing, font, margin, and indents. Any papers not well formatted would be returned back to you, hence, I advise you review APA formatting style. I have attached a sample paper in APA format and will also post sample discussion responses in subsequent announcements.

Your initial discussion post should be a minimum of 200 words and response posts should be a minimum of 150 words. Be advised that I grade based on quality and not necessarily the number of words you post. A minimum of TWO references should be used for your initial post. For your response post, you do not need references as personal experiences would count as response posts. If you however cite anything from the literature for your response post, it is required that you cite your reference. You should include a minimum of THREE references for papers in this course. Please note that references should be no more than 5 years old except recommended as a resource for the class. Furthermore, for each discussion board question, you need ONE initial substantive response and TWO substantive responses to either your classmates or your instructor for a total of THREE responses. There are TWO discussion questions each week, hence, you need a total minimum of SIX discussion posts for each week. I usually post a discussion question each week. You could also respond to these as it would count towards your required SIX discussion posts for the week.

I understand this is a lot of information to cover in 5 weeks, however, the Bible says in Philippians 4:13 that we can do all things through Christ that strengthens us. Even in times like this, we are encouraged by God’s word that we have that ability in us to succeed with His strength. I pray that each and every one of you receives strength for this course and life generally as we navigate through this pandemic that is shaking our world today. Relax and enjoy the course!

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