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Assignment NURS 6630 Neurotransmitters and Receptor Theory

Assignment: NURS 6630 Neurotransmitters and Receptor Theory

Receptors and neurotransmitters are like a lock-and-key system. Just as it takes the right key to open a
specific lock, it takes the right neurotransmitter to bind to a specific receptor. Not surprisingly, as it
concerns psychopharmacology, the pharmacotherapeutics that are prescribed must trigger the release
of certain neurotransmitters that bind to the correct receptors in order to elicit a favorable response for
the patient. The mechanism of this binding and the response that follows reflects receptor theory and
lies at the foundation of pharmacology.
This week, you will continue your examination of neuroanatomy and neuroscience as you engage with
you colleagues in a Discussion. You will also explore the potential impacts of foundational neuroscience
on the prescription of pharmacotherapeutics.
Learning Objectives
Students will:
 Analyze the agonist-to-antagonist spectrum of action of psychopharmacologic agents
 Compare the actions of g couple proteins to ion gated channels
 Analyze the role of epigenetics in pharmacologic action
 Analyze the impact of foundational neuroscience on the prescription of medications

Learning Resources

Required Readings (click to expand/reduce)

Camprodon, J. A., & Roffman, J. L. (2016). Psychiatric neuroscience: Incorporating pathophysiology into
clinical case formulation. In T. A. Stern, M. Favo, T. E. Wilens, & J. F. Rosenbaum. (Eds.), Massachusetts
General Hospital psychopharmacology and neurotherapeutics (pp. 1–19). Elsevier.

Required Media (click to expand/reduce)

The University of British Columbia. (n. d.). Neuroanatomy videos. http://neuroanatomy.ca/videos.html
Note: Please review all of the media under the neuroanatomy series.

Optional Resources (click to expand/reduce)

Pathopharmacology: Disorders of the Nervous System: Exploring the Human Brain
Dr. Norbert Myslinski reviews the structure and function of the human brain. Using human brains, he
examines and illustrates the development of the brain and areas impacted by disorders associated with
the brain. (15m)
Accessible player
Introduction to Advanced Pharmacology
In this media presentation, Dr. Terry Buttaro, associate professor of practice at Simmons School of
Nursing and Health Sciences, discusses the importance of pharmacology for the advanced practice
nurse. (6m)
Accessible player

Discussion: Foundational Neuroscience
As a psychiatric nurse practitioner, it is essential for you to have a strong background in foundational
neuroscience. In order to diagnose and treat patients, you must not only understand the
pathophysiology of psychiatric disorders but also how medications for these disorders impact the
central nervous system. These concepts of foundational neuroscience can be challenging to understand.
Therefore, this Discussion is designed to encourage you to think through these concepts, develop a
rationale for your thinking, and deepen your understanding by interacting with your colleagues.

Photo Credit: Getty Images/Cultura RF
For this Discussion, review the Learning Resources and reflect on the concepts of foundational
neuroscience as they might apply to your role as the psychiatric mental health nurse practitioner in
prescribing medications for patients.
By Day 3 of Week 2
Post a response to each of the following:
1. Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including
how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic
2. Compare and contrast the actions of g couple proteins and ion gated channels.

Assignment NURS 6630 Neurotransmitters and Receptor Theory

Assignment NURS 6630 Neurotransmitters and Receptor Theory

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3. Explain how the role of epigenetics may contribute to pharmacologic action.

4. Explain how this information may impact the way you prescribe medications to patients. Include
a specific example of a situation or case with a patient in which the psychiatric mental health
nurse practitioner must be aware of the medication’s action.
Read a selection of your colleagues' responses.
By Day 6 of Week 2
Respond to at least two of your colleagues on two different days in one of the following ways:
 If your colleagues’ posts influenced your understanding of these concepts, be sure to share how
and why. Include additional insights you gained.
 If you think your colleagues might have misunderstood these concepts, offer your alternative
perspective and be sure to provide an explanation for them. Include resources to support your
Note: For this Discussion, you are required to complete your initial post before you will be able to view
and respond to your colleagues’ postings. Begin by clicking on the "Post to Discussion Question" link and
then select "Create Thread" to complete your initial post. Remember, once you click on Submit, you
cannot delete or edit your own posts, and you cannot post anonymously. Please check your post carefully
before clicking on Submit!
Submission and Grading Information
Grading Criteria

To access your rubric:
Week 2 Discussion Rubric

Post by Day 3 of Week 2 and Respond by Day 6 of Week 2

To Participate in this Discussion:
Week 2 Discussion

What’s Coming Up in Week 3?

Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty Images

Next week, you will explore medication adherence and strategies to help overcome non-adherence to
pharmacotherapeutics. You will also complete a Quiz that addresses the content covered throughout
this module.
Next Week

To go to the next week:

Important information for writing discussion questions and participation

Hi Class,

Please read through the following information on writing a Discussion question response and participation posts.

Contact me if you have any questions.

Important information on Writing a Discussion Question

  • Your response needs to be a minimum of 150 words (not including your list of references)
  • There needs to be at least TWO references with ONE being a peer reviewed professional journal article.
  • Include in-text citations in your response
  • Do not include quotes—instead summarize and paraphrase the information
  • Follow APA-7th edition
  • Points will be deducted if the above is not followed

Participation –replies to your classmates or instructor

  • A minimum of 6 responses per week, on at least 3 days of the week.
  • Each response needs at least ONE reference with citations—best if it is a peer reviewed journal article
  • Each response needs to be at least 75 words in length (does not include your list of references)
  • Responses need to be substantive by bringing information to the discussion or further enhance the discussion. Responses of “I agree” or “great post” does not count for the word count.
  • Follow APA 7th edition
  • Points will be deducted if the above is not followed

Welcome to class

Hello class and welcome to the class and I will be your instructor for this course. This is a -week course and requires a lot of time commitment, organization, and a high level of dedication. Please use the class syllabus to guide you through all the assignments required for the course. I have also attached the classroom policies to this announcement to know your expectations for this course. Please review this document carefully and ask me any questions if you do. You could email me at any time or send me a message via the “message” icon in halo if you need to contact me. I check my email regularly, so you should get a response within 24 hours. If you have not heard from me within 24 hours and need to contact me urgently, please send a follow up text to.

I strongly encourage that you do not wait until the very last minute to complete your assignments. Your assignments in weeks 4 and 5 require early planning as you would need to present a teaching plan and interview a community health provider. I advise you look at the requirements for these assignments at the beginning of the course and plan accordingly. I have posted the YouTube link that explains all the class assignments in detail. It is required that you watch this 32-minute video as the assignments from week 3 through 5 require that you follow the instructions to the letter to succeed. Failure to complete these assignments according to instructions might lead to a zero. After watching the video, please schedule a one-on-one with me to discuss your topic for your project by the second week of class. Use this link to schedule a 15-minute session. Please, call me at the time of your appointment on my number. Please note that I will NOT call you.

Please, be advised I do NOT accept any assignments by email. If you are having technical issues with uploading an assignment, contact the technical department and inform me of the issue. If you have any issues that would prevent you from getting your assignments to me by the deadline, please inform me to request a possible extension. Note that working fulltime or overtime is no excuse for late assignments. There is a 5%-point deduction for every day your assignment is late. This only applies to approved extensions. Late assignments will not be accepted.

If you think you would be needing accommodations due to any reasons, please contact the appropriate department to request accommodations.

Plagiarism is highly prohibited. Please ensure you are citing your sources correctly using APA 7th edition. All assignments including discussion posts should be formatted in APA with the appropriate spacing, font, margin, and indents. Any papers not well formatted would be returned back to you, hence, I advise you review APA formatting style. I have attached a sample paper in APA format and will also post sample discussion responses in subsequent announcements.

Your initial discussion post should be a minimum of 200 words and response posts should be a minimum of 150 words. Be advised that I grade based on quality and not necessarily the number of words you post. A minimum of TWO references should be used for your initial post. For your response post, you do not need references as personal experiences would count as response posts. If you however cite anything from the literature for your response post, it is required that you cite your reference. You should include a minimum of THREE references for papers in this course. Please note that references should be no more than 5 years old except recommended as a resource for the class. Furthermore, for each discussion board question, you need ONE initial substantive response and TWO substantive responses to either your classmates or your instructor for a total of THREE responses. There are TWO discussion questions each week, hence, you need a total minimum of SIX discussion posts for each week. I usually post a discussion question each week. You could also respond to these as it would count towards your required SIX discussion posts for the week.

I understand this is a lot of information to cover in 5 weeks, however, the Bible says in Philippians 4:13 that we can do all things through Christ that strengthens us. Even in times like this, we are encouraged by God’s word that we have that ability in us to succeed with His strength. I pray that each and every one of you receives strength for this course and life generally as we navigate through this pandemic that is shaking our world today. Relax and enjoy the course!

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